Granulomatous Dermatitis Characterized by the Manifestation of Tumor and Plaque Lesions Subsequent to Herpes Zoster: A Case Series

BAYRAMGÜRLER D., DEMİRBAŞ A., Durdu M., ASLANKOÇ G. E., Eruyar T., Demirkesen C.

Dermatology Practical and Conceptual, cilt.14, sa.2, 2024 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 14 Sayı: 2
  • Basım Tarihi: 2024
  • Doi Numarası: 10.5826/dpc.1402a129
  • Dergi Adı: Dermatology Practical and Conceptual
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Directory of Open Access Journals
  • Anahtar Kelimeler: Granulomatous reaction, Postherpetic isotopic response, Tumor
  • Kocaeli Üniversitesi Adresli: Evet

Özet

Wolf's isotopic response is a phenomenon where a healed skin condition reappears at the same site, causing a new condition. The cause is unknown, but it is suggested to be an immunosuppressed region [1-3]. This area becomes susceptible to infections, tumors, and immune disorders. Chronic lymphedema, herpetic infections, vaccinations, and physical injuries can damage the cutaneous site, making it vulnerable. The most common isotopic response is PHIR, which is characterized by papules or plaques, patchy or nodular lesions, and hyperpigmentation [1-4]. Most cases have immunosuppressive and hematological malignancies, and both cases have hematological malignancies [1-5]. Topical steroids are commonly used in treating PHIR-GD cases [1-5], but no case has been treated with intralesional steroids. In conclusion, PHIR-GD can cause tumoral lesions, and intralesional corticosteroid therapy can be used for tumor management.