Deregulated Levels of the NF-kappa B1, NF-kappa B2, and Rel Genes in Ukrainian Patients with Leukemia and Lymphoma in the Post-Chernobyl Period

SAVLI, HAKAN; Akkoyunlu, Ramis; ÇİNE, NACİ; Gluzman, Daniil; Zavelevich, Michael; Sklyarenko, Lilia; Koval, Stella; Sunnetci, DENİZ

doi:10.4274/tjh.2014.0190

Deregulated Levels of the NF-kappa B1, NF-kappa B2, and Rel Genes in Ukrainian Patients with Leukemia and Lymphoma in the Post-Chernobyl Period

SAVLI H., Akkoyunlu R. U., ÇİNE N., Gluzman D. F., Zavelevich M. P., Sklyarenko L. M., ...Daha Fazla

TURKISH JOURNAL OF HEMATOLOGY, cilt.33, sa.1, ss.8-14, 2016 (SCI-Expanded, Scopus, TRDizin)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 33 Sayı: 1
Basım Tarihi: 2016
Doi Numarası: 10.4274/tjh.2014.0190
Dergi Adı: TURKISH JOURNAL OF HEMATOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
Sayfa Sayıları: ss.8-14
Kocaeli Üniversitesi Adresli: Evet

Özet

Objective: Nuclear factor kappa B (NF-kappa B) is an important transcription factor in cancer and NF-kappa B activation has been seen in angiogenesis, tumor progression, and metastasis. Relationships between specific NF-kappa B gene networks, leukemogenesis, and radiation exposure are still unknown. Our aim was to study the expression levels of the NF-kappa B1, NF-kappa B2, and Rel genes in hematological malignancies in the post-Chernobyl period.