Deregulated Levels of the NF-kappa B1, NF-kappa B2, and Rel Genes in Ukrainian Patients with Leukemia and Lymphoma in the Post-Chernobyl Period


SAVLI H. , Akkoyunlu R. U. , ÇİNE N. , Gluzman D. F. , Zavelevich M. P. , Sklyarenko L. M. , et al.

TURKISH JOURNAL OF HEMATOLOGY, cilt.33, ss.8-14, 2016 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 33 Konu: 1
  • Basım Tarihi: 2016
  • Doi Numarası: 10.4274/tjh.2014.0190
  • Dergi Adı: TURKISH JOURNAL OF HEMATOLOGY
  • Sayfa Sayısı: ss.8-14

Özet

Objective: Nuclear factor kappa B (NF-kappa B) is an important transcription factor in cancer and NF-kappa B activation has been seen in angiogenesis, tumor progression, and metastasis. Relationships between specific NF-kappa B gene networks, leukemogenesis, and radiation exposure are still unknown. Our aim was to study the expression levels of the NF-kappa B1, NF-kappa B2, and Rel genes in hematological malignancies in the post-Chernobyl period.