Mitomycin-C prevents reformation of intra-abdominal adhesions after adhesiolysis

Cubukcu A., Alponat A., Gonullu N.

SURGERY, cilt.131, sa.1, ss.81-84, 2002 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 131 Sayı: 1
  • Basım Tarihi: 2002
  • Doi Numarası: 10.1067/msy.2002.118316
  • Dergi Adı: SURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.81-84
  • Kocaeli Üniversitesi Adresli: Hayır

Özet

Background. Prevention of adhesions is central to surgical practice, because they cause significant morbidity. Inhibition of fibroblast proliferation is a way to prevent adhesions. Mitomycin-C (MMC) (Kyowa- Hakko-Kogyo Co, Ltd, Tokyo, Japan) is an alkylating agent that also inhibits fibroblast proliferation for up to a few weeks. We investigated the effect of MMC on the prevention of adhesion reformation.