Mitomycin-C prevents reformation of intra-abdominal adhesions after adhesiolysis


Cubukcu A., Alponat A., Gonullu N.

SURGERY, cilt.131, ss.81-84, 2002 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 131 Konu: 1
  • Basım Tarihi: 2002
  • Doi Numarası: 10.1067/msy.2002.118316
  • Dergi Adı: SURGERY
  • Sayfa Sayıları: ss.81-84

Özet

Background. Prevention of adhesions is central to surgical practice, because they cause significant morbidity. Inhibition of fibroblast proliferation is a way to prevent adhesions. Mitomycin-C (MMC) (Kyowa- Hakko-Kogyo Co, Ltd, Tokyo, Japan) is an alkylating agent that also inhibits fibroblast proliferation for up to a few weeks. We investigated the effect of MMC on the prevention of adhesion reformation.