Evaluation of prophylactic and therapeutic effects of sildenafil on acute radiation proctitis in rats(1)

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Yavuz E., Ercan G., Karagulle O. O., Bayrak B., Biricik A., Ercetin C., ...More

ACTA CIRURGICA BRASILEIRA, vol.33, no.4, pp.362-374, 2018 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 33 Issue: 4
  • Publication Date: 2018
  • Doi Number: 10.1590/s0102-865020180040000008
  • Journal Name: ACTA CIRURGICA BRASILEIRA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.362-374
  • Keywords: Sildenafil Citrate, Proctitis, Inflammation, Ultrastructure, Rats, PHOSPHODIESTERASE-5 INHIBITORS, RAT MODEL, INJURY, REPERFUSION, ACTIVATION, EXPRESSION, CYTOKINES, SYMPTOMS, ISCHEMIA, CITRATE
  • Kocaeli University Affiliated: Yes

Abstract

Purpose: To investigate the prophylactic and therapeutical effects of sildenafil in a model of acute radiation proctitis (ARP).