Evidence for the involvement of neuronal nitric oxide synthase and soluble guanylate cyclase on cognitive functions in rats


Komsuoglu-Celıkyurt I., Göçmez S. S. , Mutlu O. , Gacar N., Arıcıoğlu F., Utkan T.

LIFE SCIENCES, cilt.89, ss.905-910, 2011 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 89
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1016/j.lfs.2011.09.017
  • Dergi Adı: LIFE SCIENCES
  • Sayfa Sayısı: ss.905-910

Özet

Aims: The influence of 3-bromo-7-nitroindazole (3-Br 7-NI), a potent and selective neuronal nitric oxide synthase (nNOS) inhibitor, and [1H-[1,2,4]-oxadiazole[4,3a]-quinoxaline-1-one] (ODQ), a highly selective, irreversible inhibitor of soluble guanylate cyclase (sGC), on working and reference memory and emotional learning was investigated in rats.