EANS2024, Sofya, Bulgaristan, 13 - 17 Ekim 2024, (Tam Metin Bildiri)
Background: Cerebrospinal fluid (CSF) rhinorrhea is the leakage of active CSF due to a defect in the skull base, causing clear fluid flow from the nose, resulting in disruption of the arachnoid, dura mater, and sinonasal mucosa. One of the treatment methods is surgical treatment, where the surgical approach is determined based on the localization of the leakage. The aim of our study is to investigate the results of cases of CSF rhinorrhea, repaired using a transnasal endoscopic approach and factors that may affect surgical success. Methods: Between January 2004 and January 2024, patients with CSF rhinorrhea treated at a single tertiary center, were retrospectively screened. Results: The study includes 62 cases, 52 patients. Recurrence occurred in 9 patients, with 8 patients undergoing surgery twice and 1 patient three times. The mean age was 40.8 and the number of female cases was 38, number of male patients was 24, respectively equals to 61,2% female and 38,7% male of all patients. A combined approach was applied in 1 case. Trauma history was present in 19 cases. The location of bone defects was as following by the decreasing order: ethmoid, frontal, sphenoid sinus, and clival region. Ethmoid and frontal defects were present together in 4 cases, and ethmoid and clival defects were present together in 1 case. A multi-layer closure technique was applied in all patients for defect repair, and lumbar drainage was applied in 37 cases. An encephalocele sac was observed intraoperatively in 25 cases. The mean follow-up duration was 68.07 ( 70.078) months. Conclusions: It has been shown that, repairing a CSF rhinorrhea, successful surgical outcomes can be achieved with accurate localization of the defect area and multi-layer closure of the dural defect. Studies involving more cases and specific comparisons could yield more precise results.