Haplotype Analysis of Vitamin D Receptor (VDR) Gene in Breast Cancer Patients

Ergul E., Simsek T., Uren N., Korak T., Simsek H. U., Cine N., ...More

CLINICAL LABORATORY, vol.67, no.6, pp.1421-1427, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 67 Issue: 6
  • Publication Date: 2021
  • Doi Number: 10.7754/clin.lab.2020.200931
  • Journal Name: CLINICAL LABORATORY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
  • Page Numbers: pp.1421-1427
  • Keywords: breast cancer, haplotype analysis, polymorphism, VDR gene, POLYMORPHISMS, RISK, ASSOCIATION, VARIANTS, DISEASE, BSMI
  • Kocaeli University Affiliated: Yes

Abstract

Background: The aim of the study was to evaluate the role of well-characterized vitamin D receptor (VDR) gene polymorphisms, BsmI (rs 1544410), ApaI (rs 7975232), TaqI (rs 731236), and FokI (rs 10735810) and their haplotypes in the pathogenesis of breast cancer in Turkish women.