A 59-year-old female was hospitalised with the diagnosis of infective endocarditis. On the fifth day of her antibiotic treatment, she experienced an anterior ST segment elevation myocardial infarction. Emergency transthoracic echocardiography showed that the vegetation on the aortic valve did not exist anymore. It was thought to be an embolic myocardial infarction. Primary percutaneous coronary intervention with conventional balloon angioplasty was performed. TIMI-3 flow was obtained after intervention. Antibiotic treatment was continued for 6 weeks. She was uneventful at the end of the 3-month follow-up. (C) 2006 Elsevier Ireland Ltd. All rights reserved.