The cardioprotective effects of thoracal epidural anesthesia are induced by the expression of vascular endothelial growth factor and inducible nitric oxide synthase in cardiopulmonary bypass surgery


Gonca S. , Kilickan L., Dalcik C., Dalcik H., Byindir O.

JOURNAL OF CARDIOVASCULAR SURGERY, cilt.48, ss.93-102, 2007 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 48 Konu: 1
  • Basım Tarihi: 2007
  • Dergi Adı: JOURNAL OF CARDIOVASCULAR SURGERY
  • Sayfa Sayıları: ss.93-102

Özet

Aim The cardioprotective effects of thoracal epidural anesthesia (TEA) are induced by the expression of vascular endothelial growth factor (VEGF) and inducible nitric oxide synthase (i-NOS) in cardiopulmonary bypass (CPB) surgery. When general anaesthesia (GA) is combined with TEA during coronary artery bypass graft, we investigated whether TEA together with GA play a role on VEGF and i-NOS expression in human heart tissue in cardiac ischemia.