Usefulness of Novel Martin/Hopkins and Sampson Equations over Friedewald Equation in Cardiology Outpatients: A CVSCORE-TR Substudy.

Dinc Asarcikli L., Kis M., Sinan Güvenc T., Tosun V., Acar B., Avci Demir F., ...More

International journal of clinical practice, vol.75, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 75
  • Publication Date: 2021
  • Doi Number: 10.1111/ijcp.14090
  • Journal Name: International journal of clinical practice
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, CINAHL, EMBASE, International Pharmaceutical Abstracts, MEDLINE
  • Kocaeli University Affiliated: Yes


Background and aims The Friedewald equation (LDL-Cf) is known to produce inaccurate estimations of low-density lipoprotein cholesterol (LDL-C) when triglycerides are high (>400 mg/dL) or LDL-C is low (<70 mg/dL). The Martin/Hopkins (LDL-Cmh) and Sampson (LDL-Cs) equations were developed to overcome these limitations, but few data are available to assess whether these equations offer incremental usefulness over LDL-Cf. Our aim was to understand whether there was any incremental usefulness of novel equations on decisions regarding patient management.