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Nuclear Medicine Seminars, vol.10, no.1, pp.117-140, 2024 (Scopus)
Myocardial perfusion imaging using positron emission tomography (PET) constitutes a non-invasive diagnostic procedure that provides crucial diagnostic and prognostic insights in the context of coronary artery disease. It enables the identification of microvascular circulation disorders in the early phases. The utilization of myocardial PET perfusion studies is on the rise, primarily owing to significant advantages compared to single photon emission tomography. These advantages include superior resolution and sensitivity, robust attenuation correction, reduced radiation exposure, and the capability for absolute quantification of stress and rest myocardial blood flow. This guide endeavors to establish standardized protocols for quantitative myocardial PET perfusion imaging and aims to provide information concerning their clinical applications and interpretation, aligning with international guidelines and relevant literature.