In this study, technical details of a Stewart platform (SP) based robotic system as an endoscope positioner and holder for endoscopic transsphenoidal surgery are presented. Inverse and forward kinematics, full dynamics, and the Jacobian matrix of the robotic system are derived and simulated in MATLAB/Simulink. The required control structure for the trajectory and position control of the SP is developed and verified by several experiments. The robotic system can be navigated using a six degrees of freedom (DOF) joystick and a haptic device with force feedback. Position and trajectory control of the SP in the joint space is achieved using a new model-free intelligent PI (iPI) controller and it is compared with the classical PID (proportional-integral-derivative) controller. Trajectory tracking experimental results showed that the tracking performance of iPI is better than that of PID and the total RMSE of the trajectory tracking is decreased by 17.64% using the iPI controller. The validity of the robotic system is proven in the endoscopic transsphenoidal surgery performed on a realistic head model in the laboratory and on a cadaver in the Institute of Forensic Medicine. The key feature of the system developed here is to operate the endoscope via the joystick or haptic device with force feedback under iPI control. Usage of this system helps surgeons in long, fatiguing, and complex operations. This system can generate new possibilities for transsphenoidal surgery such as fully automated robotic surgery systems.