Beneficial effects montelukast, cysteinyl-leukotriene receptor antagonist, on renal damage after unilateral ureteral obstruction in rats

Otunctemur, Alper; Ozbek, Emin; Cakir, Suleyman; Dursun, Murat; Cekmen, Mustafa; Polat, Emre; Ozcan, Levent; Somay, Adnan; Ozbay, Nurver

doi:10.1590/s1677-5538.ibju.2015.02.14

Beneficial effects montelukast, cysteinyl-leukotriene receptor antagonist, on renal damage after unilateral ureteral obstruction in rats

Atıf İçin Kopyala

Otunctemur A., Ozbek E., Cakir S. S. , Dursun M., Cekmen M., Polat E. C. , ...Daha Fazla

INTERNATIONAL BRAZ J UROL, cilt.41, ss.279-287, 2015 (SCI İndekslerine Giren Dergi)

Cilt numarası: 41 Konu: 2
Basım Tarihi: 2015
Doi Numarası: 10.1590/s1677-5538.ibju.2015.02.14
Dergi Adı: INTERNATIONAL BRAZ J UROL
Sayfa Sayıları: ss.279-287

Özet

Introduction: Ureteral obstruction is a common pathology and caused kidney fibrosis and dysfunction at late period. In this present, we investigated the antifibrotic and antiinflammatory effects of montelukast which is cysteinyl leukotriene receptor antagonist, on kidney damage after unilateral ureteral obstruction(UUO) in rats.