Beneficial effects montelukast, cysteinyl-leukotriene receptor antagonist, on renal damage after unilateral ureteral obstruction in rats

Otunctemur A., Ozbek E., Cakir S. S., Dursun M., Cekmen M., Polat E. C., ...More

INTERNATIONAL BRAZ J UROL, vol.41, no.2, pp.279-287, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 41 Issue: 2
  • Publication Date: 2015
  • Doi Number: 10.1590/s1677-5538.ibju.2015.02.14
  • Journal Name: INTERNATIONAL BRAZ J UROL
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.279-287
  • Kocaeli University Affiliated: Yes

Abstract

Introduction: Ureteral obstruction is a common pathology and caused kidney fibrosis and dysfunction at late period. In this present, we investigated the antifibrotic and antiinflammatory effects of montelukast which is cysteinyl leukotriene receptor antagonist, on kidney damage after unilateral ureteral obstruction(UUO) in rats.