Beneficial effects montelukast, cysteinyl-leukotriene receptor antagonist, on renal damage after unilateral ureteral obstruction in rats

Otunctemur, Alper; Ozbek, Emin; Cakir, Suleyman; Dursun, Murat; Cekmen, Mustafa; Polat, Emre; Ozcan, Levent; Somay, Adnan; Ozbay, Nurver

doi:10.1590/s1677-5538.ibju.2015.02.14

Beneficial effects montelukast, cysteinyl-leukotriene receptor antagonist, on renal damage after unilateral ureteral obstruction in rats

Otunctemur A., Ozbek E., Cakir S. S. , Dursun M., Cekmen M., Polat E. C. , ...More

INTERNATIONAL BRAZ J UROL, vol.41, pp.279-287, 2015 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 41 Issue: 2
Publication Date: 2015
Doi Number: 10.1590/s1677-5538.ibju.2015.02.14
Title of Journal : INTERNATIONAL BRAZ J UROL
Page Numbers: pp.279-287

Abstract

Introduction: Ureteral obstruction is a common pathology and caused kidney fibrosis and dysfunction at late period. In this present, we investigated the antifibrotic and antiinflammatory effects of montelukast which is cysteinyl leukotriene receptor antagonist, on kidney damage after unilateral ureteral obstruction(UUO) in rats.