Atıf İçin Kopyala
Kiraz U., Vural Ç., Turan G., Alparslan B., Dervisoglu E.
Turkish neurosurgery, cilt.32, sa.2, ss.228-236, 2022 (SCI-Expanded)
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Yayın Türü:
Makale / Tam Makale
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Cilt numarası:
32
Sayı:
2
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Basım Tarihi:
2022
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Doi Numarası:
10.5137/1019-5149.jtn.33708-21.3
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Dergi Adı:
Turkish neurosurgery
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Derginin Tarandığı İndeksler:
Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE, TR DİZİN (ULAKBİM)
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Sayfa Sayıları:
ss.228-236
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Anahtar Kelimeler:
Glioblastoma, IDH1 mutation, Immunohistochemistry, Polymerase chain reaction, Magnetic resonance imaging, CENTRAL-NERVOUS-SYSTEM, MUTATIONS, BRAIN, CLASSIFICATION, SURVIVAL, GLIOMAS, TUMORS, BIOMARKER, ANTIBODY, ATRX
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Kocaeli Üniversitesi Adresli:
Evet
Özet
AIM: To assess the presence of isocitrate dehydrogenase (IDH) 1 mutation in glioblastomas using real-time polymerase chain reaction (RT-PCR), which is the gold standard in the diagnosis of IDH1 mutation; by immunohistochemistry (IHC), which is available in most of the pathology laboratories; and by preoperative magnetic resonance imaging, which is a non-invasive method. We also investigated the relationship between these methods and their usability in routine practice.