Primary diffuse large B-cell lymphoma of the mandible: A case report

COŞKUNSES F. M., Cilasun U., Celik Topcu P., TOKUÇ B.

GERODONTOLOGY, vol.37, no.3, pp.307-311, 2020 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 37 Issue: 3
  • Publication Date: 2020
  • Doi Number: 10.1111/ger.12470
  • Journal Name: GERODONTOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, CINAHL, EMBASE, MEDLINE
  • Page Numbers: pp.307-311
  • Keywords: B-cell lymphoma, mandible, NON-HODGKINS-LYMPHOMAS, ORAL-CAVITY, MAXILLOFACIAL REGION, MALIGNANT-LYMPHOMA, HEAD, NECK
  • Kocaeli University Affiliated: Yes

Abstract

Introduction Lymphomas are a heterogeneous group of malignant neoplasms of lymphocytes and their precursor cells. Lymphoma is seen 3.5% of all intraoral malignancies and is the second most common neoplasm after the squamous cell carcinoma in the head and neck region. Diffuse large B-cell lymphomas (DLBCL), which is a subtype of non-Hodgkin lymphoma, are seen mostly in the paraoral region. Case presentation An 82-year-old woman was referred with a localised swelling of the mandibular buccal mucosa for 3 months. Excisional biopsy revealed the diagnosis of DLBCL in the mandible and chemotherapy regimen started immediately. However, patient died during treatment. Conclusions Non-Hodgkin's lymphomas would be late- or misdiagnosed in the perioral region that may result poor prognosis.