Synthesis and antimicrobial activity of some novel furyl and benzimidazole substituted benzyl ethers

OZEL GUVEN O., Erdogan T., GOKER H., YILDIZ S.

JOURNAL OF HETEROCYCLIC CHEMISTRY, vol.44, no.3, pp.731-734, 2007 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 44 Issue: 3
  • Publication Date: 2007
  • Journal Name: JOURNAL OF HETEROCYCLIC CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.731-734
  • Kocaeli University Affiliated: No

Abstract

In this study, a series of novel furyl and benzimidazole substituted benzyl ethers were synthesized and evaluated for antibacterial and antifungal activities against S. aureus, Methicillin resistant S. aureus (MRSA), E. coli, C. albicans and C. krusei. Compound 6f and 6h exhibited the most potent anti-bacterial activity with lowest MIC values of 3.12 mu g/mL against S aureus and MRSA, respectively.