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2026 - Present Whartons Jelly Kökenli Mezenkimal Kök Hücre Kaynaklı Eksozom ve Mitokondri Uygulamalarının Yaşa Bağlı Makula Dejenerasyon ve Aquaporin Profili Üzerindeki Rolünün Kuersetin ile Karşılaştırılmalı Olarak İncelenmesi
Project Supported by Higher Education Institutions , BAP Research Project
KILIÇ K. C. (Executive), DURUKSU G., ÖZTÜRK A., ALTUNTAŞ C., YAZIR Y., KILIÇ B., et al.
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2025 - Present Iron deposition-targeting brain stimulation treatment (proton transmission and transcranial electric field) preventing white matter injury in Alzheimer's disease mouse model
Project Supported by Higher Education Institutions , BAP Research Project
KIM J. (Executive), AKPINAR G., DUMAN ÖZTÜRK S., DURUKSU G.
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2024 - Present Poli(diizopropil glikolid) ve Poli(diizobütil glikolid) Nanopartikül Formülasyonları ve Toksisite Analizleri
Project Supported by Higher Education Institutions , BAP Research Project
MERT S. (Executive), MERT O., YAZIR Y., Halis F. Ö., ÇELEBİ G., GÖÇMEZ S. S., et al.
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2024 - Present Kuersetin yüklü mezenkimal kök hücre eksozomlarının ve aljinat kaplı kuersetin mikroenkapsülasyonunun PKOS granüloza hücreleri üzerindeki etkilerinin incelenmesi
Project Supported by Higher Education Institutions , BAP Research Project
FURAT S. H. (Executive), BUDAK Ö., YAZIR Y., DURUKSU G., MERT S., HALBUTOĞULLARI Z. S., et al.
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2024 - Present Mezenkimal kök hücre eksozomlarının farklı konsantrasyonlarının yaşlanma üzerine etkilerinin incelenmesi ve doz optimizasyonu
Project Supported by Higher Education Institutions , BAP Research Project
HALBUTOĞULLARI Z. S. (Executive), ÖZTÜRK A., YAZIR Y., SARIHAN M., AKPINAR G., YANAR S., et al.
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2023 - Present Wnt-beta katenin İnaktif Fenotipi Varyasyonu Gösteren Mezenkimal Kök Hücrelerin Rejeneratif Etkisinin Hepatik Fibroz Hayvan Modelinde Araştırılması
Project Supported by Higher Education Institutions , BAP Research Project
ŞİMŞEK T. (Executive), UZELLİ ŞİMŞEK H., DURUKSU G., ÖZTÜRK A., FURAT RENÇBER S. H., YAZIR Y.
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2026 - 2027 Investigation of the Effect of Mitochondrial Transfer to Adipose Tissue-Derived Mesenchymal Stem Cells on Differentiation into Brown Fat Tissue Cells
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2026 - 2026 Development of Mitochondrial Isolation Fluid that Protects Mitochondria and Supports Membrane Potential
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2025 - 2026 In Vitro Evaluation of the Wound Healing Potential of Galleria mellonella L. (Lepidoptera: Pyralidae) Hemolymph on Fibroblast Cells
Project Supported by Higher Education Institutions , BAP Research Project
Aslan Canatan V.(Executive), Çoğun H. Y., Turgut F., Tunçso B., Yazır Y., Satıcıoğlu I. B., et al.
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2024 - 2026 Synthesis of Dual-Targeted PDT Agents for Pancreas Cancer and Investigation of Their Diagnostic/Therapeutic Efficacy under In Vitro and In Vivo Conditions
R&D Project of Group B
Göksel Şahin M. (Executive), Yazır Y., Balçık Erçin P., Duruksu G., Utkan T., Özer C., et al.
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2022 - 2026 Investigation of the Roles of Brain Extracellular Matrix Aging in Alzheimer's Disease 'Independently of Cellular Senescence
TUBITAK Project , 1001 - Program for Supporting Scientific and Technological Research Projects
Yazır Y. (Executive), Duruksu G., Halbutoğulları Z. S., Öztürk A., Kılıç K. C.
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2024 - 2025 M1 polarize makrofaj kaynaklı inflamatuar mikroçevreyle oluşturulan in vitro OA modelinde Wharton jelly kaynaklı MKHden izole edilen mitokondri transferinde AGEslerin mitokondrial biyogenez ve tedavi başarısı üzerine etkilerinin incelenmesi
Project Supported by Higher Education Institutions , BAP Research Project
DURUKSU G. (Executive), HUNÇ F., YAZIR Y., Altuntaş C., AKBULUT C.
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2024 - 2025 Evaluation of the Efficacy of Dental Pulp-Derived Mesenchymal Stem Cell Sheet Technology in Sharp Trauma of the Facial Nerve
TUBITAK Project , 1002 - Quick Support Program
Kara A.(Executive), Öncel Duman B., Duruksu G., Elden H., Doğanay S.
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2024 - 2025 Evaluation of the Efficacy of Dental Pulp-Derived Mesenchymal Stem Cell Sheet Technology in a Sharp Trauma Model of the Recurrent Laryngeal Nerve
TUBITAK Project , 1002 - Quick Support Program
Kara A.(Executive), Erdem A. F., Öncel Duman B., Duruksu G., Elden H., Doganay S., et al.
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2024 - 2025 Investigation of the Effect of Wharton Gel-Derived Mesenchymal Stem Cells on 1.1B4 Cells Cultured on Oxygen-Releasing Biomaterial
TUBITAK Project , 1002 - Quick Support Program
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2023 - 2025 Production and In Vitro Application of PHBV/Modified TPS Films as Wound Dressings
Research Project of the Presidency of Turkey Health Institutes (TÜSEB)
Mert S. (Executive), Yazır Y., Duruksu G., Liman G., Halbutoğulları Z. S.
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2023 - 2025 Biyomalzeme Laboratuvarı Araştırma Projelerine Altyapı Desteği
Project Supported by Higher Education Institutions , BAP Infrastructure
ERDEM A. (Executive), GÜNDOĞDU Ö., DURUKSU G.
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2022 - 2025 In vitro osteoartrit modelinde mitokondri transferinin hücre canlılığı ve makrofaj polarizasyonuna etkilerinin incelenmesi
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2022 - 2025 Yaşa Bağlı Makula Dejenerasyon Doku Modelinde Erişkin Kök Hücre Kaynaklı Mitokondri Transferinin Etkisinin İncelenmesi
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2023 - 2024 Investigation of the Effects of Induced Wharton's Jelly-Derived Mesenchymal Stem Cell Exosomes on Testicular Functions in an Azoospermia Model
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2023 - 2024 Investigation of the Immunometabolic Effects of Mitochondrial Transfer on Macrophage Polarization and Chondrocytes within the Biopathogenesis of Osteoarthritis
TUBITAK Project , 1002 - Quick Support Program
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2023 - 2024 Aljinat Mikropartiküllerin Boyutu Üzerinde Çözücü Etkisinin İncelenmesi
Project Supported by Higher Education Institutions , BAP Infrastructure
MERT S. (Executive), DURUKSU G., ASRİ H., MERT O.
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2023 - 2024 Over Fizyolojik Yaşlanma Modelinde Kemik İliği Mezenkimal Kök Hücre Kaynaklı Mitokondri Uygulamasının Overler Üzerine Etkilerinin Araştırılması
Project Supported by Higher Education Institutions , BAP Infrastructure
UTKAN T. (Executive), HALBUTOĞULLARI Z. S., DURUKSU G., Furat Rençber H. s., Utkan Korun z. E.
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2023 - 2024 Investigation of the Effects of Exosomes Derived from Induced Adipose-Derived Mesenchymal Stem Cells on Alzheimer's Disease-Modeled SH-SY5Y Human Neuroblastoma Cell Line and Aβ-Degradation
TUBITAK Project , 1002 - Quick Support Program
Gacar G. (Executive), Halbutoğulları Z. S., Duruksu G.
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2021 - 2024 Development of High-Adhesion Gelatin-Based Surgical Sealants Enhanced with Visible Light-Crosslinkable Catechol-Functionalized PEG and Alginat
TUBITAK Project , 1001 - Program for Supporting Scientific and Technological Research Projects
Erdem A. (Executive), Duruksu G., Yazır Y.
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2019 - 2024 Targeted Poly(Asymmetrically Substituted Glycolide) Star Nanosystems Loaded with Anti-miR-1908 and Temozolomide for Brain Tumor Treatment
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2022 - 2023 Investigation of the Effect of anti-CD2 Antibody Coated Wharton Jelly Mesenchymal Stem Cells on the Stimulated CD3+ T Lymphocytes and the Beta Cell Death
Research Project of the Presidency of Turkey Health Institutes (TÜSEB)
Yazır Y. (Executive), Duruksu G.
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2022 - 2023 Investigation of the Effects of M1/M2 Polarized Tumor-Associated Macrophage-Derived Inflammation on Prostate Cancer Cell Integrated Stress Response and Carcinogenesis and Its Role in Antiandrogen Drug Resistance
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2022 - 2023 Sıçan Nöral Kök Hücreler ve Hidrojen Peroksit ile Oksidatif Stres Oluşturulması Sonrası Askorbik Asitin İnflamasyona Olan Etkisinin İncelenmesi
Project Supported by Higher Education Institutions , BAP Infrastructure
GACAR G. (Executive), KILIÇ K. C., özcan o., DURUKSU G., ÖZTÜRK A., ASLAN D., et al.
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2022 - 2023 Investigation of the Regenerative Effects of Mesenchymal Stem Cells Exhibiting an Inactive Wntbeta-catenin Phenotype Variation in an Animal Model of Hepatic Fibrosi
Project Supported by Higher Education Institutions , BAP Research Project
Duruksu G., Yazır Y., Furat Rençber S. H., Öztürk A., Uzelli Şimşek H., Şimşek T. (Executive)
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2022 - 2023 Erişkin Kök Hücrelerden Elde Edilmiş Mitokondrilerin Transferinin Oksidatif Stres Oluşturulmuş Retinal Hücreler Üzerindeki Etkilerinin Ksantofil Lutein ile Karşılaştırılmalı Olarak İncelenmesi
Project Supported by Higher Education Institutions , BAP Infrastructure
DURUKSU G. (Executive), KILIÇ K. C., YAZIR Y., ÖZTÜRK A., Özcan O.
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2021 - 2023 Aljinat Mikrokapsüllerde Baryum Ba2 iyonlarının BSA Salım Hızına Etkisinin İncelenmesi
Project Supported by Higher Education Institutions , BAP Infrastructure
MERT S. (Executive), DURUKSU G., HALBUTOĞULLARI Z. S., UÇKAN F.
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2021 - 2023 Göbek Kordonu Kökenli ve Endometriyum Kökenli Mezenkimal Kök Hücrelerinin Tip 1 Diabetes Mellitus Hastalığı Üzerindeki Etkilerinin İncelenmesi
Project Supported by Higher Education Institutions , BAP Infrastructure
YAZIR Y. (Executive), DURUKSU G., ÖZTÜRK A., KILIÇ K. C., ÖZCAN O.
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2021 - 2022 Investigation of the therapeutic efficacy of androgen receptor inhibitor apalutamide on hormone sensitive prostate cancer cell line (LNCaP) with inflammation and unfolded protein response
Project Supported by Higher Education Institutions , BAP Research Project
Dillioğlugil M. Ö. (Executive), Hunç F., Duruksu G.
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2019 - 2022 Organocatalytic Synthesis of Poly(asymmetrically substituted glycolide) Homo- and Copolymers at Room Temperature
TUBITAK Project , 1001 - Program for Supporting Scientific and Technological Research Projects
Mert O. (Executive), Duruksu G., Yazır Y.
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2017 - 2022 Generation of Spinal Muscular Atrophy Disease Animal Model by Adult Stem Cells and Demonstration of its Functionality
TUBITAK Project , 1003 - Priority Areas R&D Projects Support Program
Duruksu G. (Executive), Yazır Y., Utkan T., Gacar G., Teke K.
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2020 - 2021 Mezenkimal kök hücre içeren farklı aljinat mikrokapsüllerinin SEM ile morfolojik analizleri
Project Supported by Higher Education Institutions , BAP Infrastructure
YAZIR Y. (Executive), DURUKSU G., KILIÇ K. C., ÖZTÜRK A.
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2020 - 2021 Endokrin Pankreans Organoid Yaşlanma Modelinde Mitokondri Hasarının İncelenmesi
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2020 - 2021 Hedefli & Suda Çözünebilir Fotodinamik Terapi Ajanı Sentezlenmesi
Project Supported by Higher Education Institutions , BAP Infrastructure
GÖKSEL ŞAHİN M. (Executive), HALBUTOĞULLARI Z. S., DURUKSU G., GACAR G., YAZIR Y., EKİNEKER G., et al.
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2018 - 2020 Investigation of the Therapeutic Effects of Wharton's Jelly-Derived Mesenchymal Stem Cell Exosomes Induced by a Cisplatin-Stressed Renal Microenvironment on Cisplatin Nephrotoxicity
TUBITAK Project , 1001 - Program for Supporting Scientific and Technological Research Projects
Oyar E. Ö.(Executive), Yazir Y., Duruksu G., Yardimoğlu Yilmaz M.
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2018 - 2019 Clinical and Histopathological Investigation of the Effects of Citicoline-Containing Eye Drops on Wound Healing via Antioxidant Mechanisms and Their Role in Cell Survival in an Experimental UVB-Induced Corneal Damage Model
Project Supported by Higher Education Institutions , BAP Research Project
Duruksu G., Yüksel N. (Executive)
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2018 - 2019 İMMORTAL BETA HÜCRE HATTI KAYNAKLI MİKROVEZİKÜLLERİN MEZENKİMAL KÖK HÜCRELERİN İNSÜLİN ÜRETEN HÜCRELERE FARKLILAŞMA POTANSİYELİNE ETKİSİ
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2018 - 2019 KALP DOKUSUNDA YAŞLANMAYA BAĞLI PERİSİT FONKSİYONLARININ İMMÜNOHİSTOKİMYASAL OLARAK İNCELENMESİ
Project Supported by Higher Education Institutions , BAP Research Project
KOMSUOĞLU ÇELİKYURT F. İ. (Executive), YAZIR Y., URAL D., GÜRSOY ÖZDEMİR Y., UTKAN T., GACAR G., et al.
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2016 - 2019 The Effects of Resveratrol on Learning and Memory Functions in a Streptozotocin-Induced Diabetic Vascular Dementia Model in Rats
Project Supported by Higher Education Institutions , BAP Research Project
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2017 - 2018 ÖNGÖRÜLEMEYEN KRONİK HAFİF STRESLE İNDÜKLENEN SIÇAN DEPRESYON MODELİNDE İNFLİKSİMAB, RESVERATROL VE KUERSETİNİN VAS DEFERENS FONKSİYONEL YANITLARI ÜZERİNDEKİ ANTİOKSİDAN VE ANTİİNFLAMATUAR ETKİLERİNİN ARAŞTIRILMASI
Project Supported by Higher Education Institutions , BAP Research Project
DEMİRTAŞ ŞAHİN T. (Executive), UTKAN T., YAZIR Y., GÖÇMEZ S. S., DURUKSU G.
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2017 - 2018 BETA HÜCRELERİNİN ENERJİ METABOLİZMASI VE İNSÜLİN SALGISINA İLERİ GLİKASYON SON ÜRÜNLERİNİN (AGE) ETKİLERİNİN İN VİTRO ORTAMDA İNCELENMESİ
Project Supported by Higher Education Institutions , BAP Research Project
DURUKSU G. (Executive), YAZIR Y.
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2017 - 2018 TÜKENME TEHDİDİ ALTINDAKİ AMSONİA ORİENTALİS MAVİ YILDIZ? BİTKİSİNDEN ANTİ-KANSER ÖZELLİKTEKİ SEKONDER METABOLİTLERİN ELDESİ, SAFLAŞTIRILMASI VE BUNLARIN KANSERLİ HÜCRELER ÜZERİNE ETKİ MEKANİZMALARININ ARAŞTIRILMASI
Project Supported by Higher Education Institutions , BAP Research Project
ÖZEN F. (Executive), DURUKSU G., ACEMİ A.
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2017 - 2018 PLEUROTUS OSTREATUS BETA-GLUKANIN MEZENKİMAL KÖK HÜCRELERİ ÜZERİNDEKİ OSTEOJENİK FARKLILAŞMAYA ETKİLERİNİN İNCELENMESİ
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2017 - 2017 The Impact of Calcium Silicate Cements on Healthy and Lipoteichoic Acid-Infected Dental Pulp Stem Cells
Project Supported by Higher Education Institutions , BAP Research Project
Sepet E.(Executive), Aktaş E., Irez T., Yazır Y., Duruksu G., Ergüven M.
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2013 - 2017 Yeni bor bazlı biyomalzemelerin sentezleri, formülasyonları ve teronostik etkilerinin incelenmesi
TUBITAK Project , 1001 - Program for Supporting Scientific and Technological Research Projects
Mert O. (Executive), YILDIZ U., Kayan A., Duruksu G., Karaöz E.
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2013 - 2015 Experimental In Vitro Model for the Development of Type 1 Diabetes
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2012 - 2015 Generetion of Functionally Insulin Secreting Cells by Transfection of Genes, Mafa Ngn3 Pax4, Responsible of Pancreatic Islet Neogenesis and Tissue Engineering Approach
TUBITAK Project , 1001 - Program for Supporting Scientific and Technological Research Projects
Duruksu G. (Executive), Karaöz E.
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2014 - 2014 İNSAN KEMİK İLİĞİ KAYNAKLI MEZENKİMAL KÖK HÜCRELERİN MEME KANSER HÜCRELERİNİN EKSOZOMLARINA GÖSTERDİĞİ KANSER KARŞITI TEPKİNİN ARAŞTIRILMASI
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2012 - 2014 Comparative Investigation of the Osteogenic Differentiation Potential of Multiple Myeloma-Derived Mesenchymal Stem Cells and Their Induced Pluripotent Kök Hücre (iPSC) Counterparts
TUBITAK Project , 1001 - Program for Supporting Scientific and Technological Research Projects
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2013 - 2013 The Effects of Exosomes Derived from Various Cancer Cell Lines on Stromal and Stem Cells
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2012 - 2012 Mezenkimal Kök Hücrelerin Tiroid Kanseri Hücre Hatları Üzerindeki Çoğalma Engelleyici Etkisinin İncelenmesi
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2011 - 2012 Expression of Recombinant Tyrosin Hydroxylase Enzyme in Mesenchymal Stem Cells Immobilized on Collagen Coated Microcarriers in Continuous Culture System
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2010 - 2012 Ratlarda deneysel olarak oluşturulan glokom modelinde intravitreal kök hücre implantasyonunun gangliyon hücre rejenerasyonu üzerine etkisi
Project Supported by Higher Education Institutions , BAP Research Project
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2011 - 2011 Mezenkimal Kök Hücreden Farklılaşmış Endotel Benzeri Hücrelerin Anjiogenez Yeteneklerinin Gerçek Zamanlı PZR ile Moleküler Düzeyde İncelenmesi
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2010 - 2010 Sıçan yağ dokusu kaynaklı mezenkimal kök hücrelerine elektroporatör kullanılarak GFP geni aktarımının optimizasyonu
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2009 - 2009 Farklı İnsan Doku Hücrelerinde Telomer Uzunluğu ve Telomeraz Aktivitesi
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2003 - 2007 Cloning, Transgenic Expression and Industrial Production Studies of the Fungal β-1,4-Mannanase Gene
Funded Projects
Funded Projects
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