Metrikler
Yayın
24
Açık Erişim
5
BM Sürdürülebilir Kalkınma Amaçları
Eğitim Bilgileri
2008 - 2012
2008 - 2012Doktora
The University of Manchester, Faculty Of Life Sciences, Birleşik Krallık
2005 - 2007
2005 - 2007Yüksek Lisans
Orta Doğu Teknik Üniversitesi, Fen Bilimleri Enstitüsü, Biyoteknoloji (Yl) (Tezli), Türkiye
2001 - 2005
2001 - 2005Lisans
Ankara Üniversitesi, Fen Fakültesi, Biyoloji Bölümü, Türkiye
Yaptığı Tezler
2012
2012Doktora
Assessment of the influence of chromatin elements on stability of recombinant protein production in amplified CHO cells
The University Of Manchester, Faculty Of Life Sciences
2007
2007Yüksek Lisans
Polymerase chain reaction (PCR) for detection of Borrelia burgdorferi sensu lato
Orta Doğu Teknik Üniversitesi, Fen Bilimleri Enstitüsü, Biyoteknoloji (Yl) (Tezli)
Araştırma Alanları
Biyoinformatik
Biyoteknoloji
Moleküler Biyoloji ve Genetik
Akademik Ünvanlar / Görevler
2017 - Devam Ediyor
2017 - Devam EdiyorDr. Öğr. Üyesi
Kocaeli Üniversitesi, Fen Edebiyat Fakültesi, Biyoloji
2013 - 2017
2013 - 2017Araştırma Görevlisi
Kocaeli Üniversitesi, Biyoloji Bölümü
Yönetimsel Görevler
2014 - Devam Ediyor
2014 - Devam EdiyorErasmus Programı Kurum Koordinatörü
Kocaeli Üniversitesi, Fen Edebiyat Fakültesi, Biyoloji
Makaleler
Tümü (14)
SCI-E, SSCI, AHCI (13)
SCI-E, SSCI, AHCI, ESCI (13)
Scopus (13)
TRDizin (1)
2025
20251. Natural Compounds and Histone Deacetylase Inhibitors: A Combined Approach Against mCRPC Cells
Alimudin J., Betts Z., Ozkan A. D.
Biomedicines
, cilt.13, sa.2, 2025 (SCI-Expanded, Scopus)
2023
20232. Long term culture promotes changes to growth, gene expression, and metabolism in CHO cells that are independent of production stability
Torres M., BETTS Z., Scholey R., Elvin M., Place S., Hayes A., et al.
Biotechnology and Bioengineering
, cilt.120, sa.9, ss.2389-2402, 2023 (SCI-Expanded, Scopus)
2023
20233. DETERMINATION OF THE EFFECT OF RUTIN ON EPITHELIAL TO MESENCHYMAL TRANSITION IN PROSTATE CANCER CELLS
Bal E., ÖZKAN A. D., Betts Z.
Acta Medica Nicomedia
, cilt.6, sa.1, ss.131-136, 2023 (TRDizin)
2023
20234. Investigation of the combined cytotoxicity induced by sodium butyrate and a flavonoid quercetin treatment on MCF-7 breast cancer cells
Betts Z., Deveci Ozkan A., Yüksel B., Alimudin J., Aydın D., Aksoy Ö., et al.
Journal of Toxicology and Environmental Health - Part A: Current Issues
, cilt.86, sa.22, ss.833-845, 2023 (SCI-Expanded, Scopus)
2023
20235. Assessing in vitro anti-cancer efficacy of sulfonated water-soluble phthalocyanine on breast and prostate cancer cells
Ozkan A. D., Betts Z., Yüksel B., Alimudin J., Aydın D., Guzel E.
JOURNAL OF PORPHYRINS AND PHTHALOCYANINES
, cilt.27, sa.1, ss.493-500, 2023 (SCI-Expanded, Scopus)
2022
20226. Anticancer Properties of Eisenia Foetida Proteins in Prostate Cancer Cells In Vitro
Ozkan A. D., Eskiler G. G., Sarıhan M., Kazan N., Aksoy Ö., Yüksel B., et al.
International Journal of Peptide Research and Therapeutics
, cilt.28, sa.4, 2022 (SCI-Expanded, Scopus)
2022
20227. Evaluation of the antioxidative and genotoxic effects of sodium butyrate on breast cancer cells
Yüksel B., Deveci Ozkan A., Aydın D., Betts Z.
Saudi Journal of Biological Sciences
, cilt.29, ss.1394-1401, 2022 (SCI-Expanded, Scopus)
2022
20228. Protective effect of Eisenia foetida coelomic fluid against oxidative damage in human endothelial cells
Kilciler Y., Ozkan A. D., BETTS Z.
TOXICOLOGICAL AND ENVIRONMENTAL CHEMISTRY
, cilt.104, sa.2, ss.307-320, 2022 (SCI-Expanded, Scopus)
2022
20229. In vitro chemo-protective effect of Eisenia foetida coelomic fluid against histone deacetylase inhibitor-induced oxidative toxicity in breast cancer cells
Ozkan A. D., Alimudin J., Kilciler Y., Yüksel B., Aksoy Ö., Betts Z.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH
, cilt.33, sa.12, ss.1728-1737, 2022 (SCI-Expanded, Scopus)
2017
201710. Improved CHO Cell Line Stability and Recombinant Protein Expression During Long-Term Culture
BETTS Z., Dickson A. J.
HETEROLOGOUS PROTEIN PRODUCTION IN CHO CELLS: METHODS AND PROTOCOLS
, cilt.1603, ss.119-141, 2017 (SCI-Expanded, Scopus)
2016
201611. Ubiquitous Chromatin Opening Elements (UCOEs) effect on transgene position and expression stability in CHO cells following methotrexate (MTX) amplification
Betts Z., Dickson A. J.
BIOTECHNOLOGY JOURNAL
, cilt.11, sa.4, ss.554-564, 2016 (SCI-Expanded, Scopus)
2015
201512. Assessment of UCOE on Recombinant EPO Production and Expression Stability in Amplified Chinese Hamster Ovary Cells
Betts Z., Dickson A. J.
MOLECULAR BIOTECHNOLOGY
, cilt.57, sa.9, ss.846-858, 2015 (SCI-Expanded, Scopus)
2015
201513. Evaluating the interaction between UCOE and DHFR-linked amplification and stability of recombinant protein expression
Betts Z., Croxford A. S., Dickson A. J.
BIOTECHNOLOGY PROGRESS
, cilt.31, sa.4, ss.1014-1025, 2015 (SCI-Expanded, Scopus)
2009
200914. Seroprevalence of bovine leptospirosis in Kayseri, Turkey and detection of leptospires by polymerase chain reaction
GÜMÜŞSOY K. S., Ozdemir V., AYDIN F., Asian O., Atabek E., lea T., et al.
Journal of Animal and Veterinary Advances
, cilt.8, sa.6, ss.1222-1229, 2009 (SCI-Expanded, Scopus)
Hakemli Bilimsel Toplantılarda Yayımlanmış Bildiriler
2019
20191. Stability of recombinant protein production in CHO cell lines: A molecular approach
BETTS Z., Place S., DICKSON A. J.
BioProNET 6th Annual Science Meeting, 3 - 04 Haziran 2019, (Özet Bildiri)
2019
20192. Molecular Mechanism of rekombinant protein production instability
BETTS Z., Ramberg V., Barsoum E., Ingrid L., Smith D., DICKSON A. J., et al.
26th ESACT Meeting, 5 - 08 Mayıs 2019, (Özet Bildiri)
2018
20183. Instability in CHO cells: Diagnosis and Cure
BETTS Z., Place S., DICKSON A. J.
BioProNET 5th Annual Science Meeting, 10 - 11 Ekim 2018, (Özet Bildiri)
2015
20154. Effect of Sodium Butyrate on the Surrounding Chromatin Environment in AMplified CHO cells
BETTS Z., Alan J D.
International Conference on Biochemistry and Molecular Biology, Paris, Fransa, 22 - 23 Nisan 2015, (Özet Bildiri)
2014
20145. Effect of transgene location on productivity and stability of recombinant protein expression
BETTS Z., Alan J D.
European Federation of Biotechnology, Focus on Frontiers in Industrial Biotechnology, Londrina, Brezilya, 17 Kasım 2014 - 19 Kasım 2013
2014
20146. Sodyum butiratin amplifiye edilmis CHO hucrelerinde rekombinant protein ekspresyonuna etkisi
BETTS Z., Alan J D.
22. Ulusal Biyoloji kongresi, Eskişehir, Türkiye, 23 - 27 Haziran 2014
2011
20117. Stability of recombinant protein production in amplified CHO cells
BETTS Z., DICKSON A. J., Croxford A. S.
22nd European Society for Animal Cell Technology Meeting, Viyana, Avusturya, 15 - 18 Mayıs 2011, (Özet Bildiri)
2010
20108. Stability of recombinant protein production in Chinese Hamster Ovary Cells
BETTS Z., Croxford A. S., DICKSON A. J.
20th Annual Conference ESACT-UK, UK Society for Cell Culture and Biotechnology, Loughborough, Birleşik Krallık, 6 - 07 Ocak 2010, (Özet Bildiri)
2009
20099. Stability of recombinant protein production in amplified Chinese hamster ovary cells
BETTS Z., DICKSON A. J., Croxford A. S.
9th Conference on Protein Expression in Animal Cells, Jackson Hole, Amerika Birleşik Devletleri, 19 - 23 Eylül 2009, (Özet Bildiri)
Kitaplar
2017
20171. Improved CHO Cell Line Stability and Recombinant Protein Expression During Long-Term Culture
BETTS Z., DICKSON A. J.
Heterologous Protein Production in CHO Cells, Paula Meleady, Editör, Springer, New-York, ss.119-141, 2017
Desteklenen Projeler
2016 - 2017
2016 - 2017YÜKSEK BASINÇLI SICAK SU EKSTRAKSİYONU İLE ELDE EDİLEN PROTEİN EKSTRELERİNİN ÇEŞİTLİ TÜMÖR HÜCRELERİ ÜZERİNE SİTOTOKSİK AKTİVİTESİNİN ARAŞTIRILMASI
Yükseköğretim Kurumları Destekli Proje , BAP Doktora
SEVİMLİ GÜR C. (Yürütücü), YEŞİL ÇELİKTAŞ Ö., BETTS Z., İLHAN E.
Burslar
2019 - 2019
2019 - 2019UKRI BBSRC Flexible Talent Mobility Account
Diğer Uluslararası Organizasyonlar
2018 - 2019
2018 - 20192219-Yurtdışı Doktora sonrası araştırma bursu
TÜBİTAK
2008 - 2012
2008 - 2012Yurt Dışı Doktora Bursu
Milli Eğitim Bakanlığı
2005 - 2007
2005 - 2007Yurt İçi Yüksek Lisans Bursu
TÜBİTAK
2002 - 2005
2002 - 2005